Mitosis in Animal and Plant Cells

In this unit, students discover how life reproduces at the cellular level, analyzing the science phenomena of how genetic information is stored in chromosomes. In this lesson, students observe mitosis in plants and animals. This page shows key components of this lesson.

Science Background for Teachers:

The science background provides teachers with more in-depth information on the phenomena students explore. Below is an excerpt from the science background section on mitosis.

Mitosis

There are several reasons why cells divide. One important reason is growth. Cell division also allows cells to repair damaged cells or replace dead cells. Finally, cells divide to reproduce, passing along genetic information to offspring.

Mitosis is a form of cell division that takes place in eukaryotic cells and results in two daughter cells, each with the same number and kind of chromosomes as the parent cell. There are four phases as a parent cell separates its replicated chromosomes into two daughter cells.

Phase 1: Prophase— When the cell is ready to divide, DNA is wrapped even more tightly, and the chromosomes become visible. Each chromosome consists of the two sister chromatids formed during replication. The nuclear membrane breaks down and the chromosomes are freed from the nucleus. Small fibers called spindle fibers begin to form on opposite sides of the cell and attach to each sister chromatid.

Phase 2: Metaphase— During metaphase, the chromosome pairs line up in the middle of the cell end-to-end. This formation ensures that each daughter cell will receive one copy of each chromosome.

Phase 3: Anaphase—Separation begins. The sister chromatids separate and the spindle fibers pull one complete set of an organism’s chromosomes to each end of the cell. For humans, 46 chromosomes move to each end of the cell. Each side receives the same number and kind of chromosomes as the parent cell.

Phase 4: Telophase—During telophase, the chromosomes reach opposite ends of the cell. Nuclear envelopes reassemble and enclose each cell’s set of chromosomes in a nucleus. The chromosomes become indistinct chromatin.

After telophase, most cells undergo a process called cytokinesis in which the rest of the cell splits apart, resulting in two separate daughter cells.

Phases in Mitosis

Cells spend more than half of their lives in interphase. This is because a lot has to happen during interphase. The cell increases in size, replicates its DNA, and builds materials needed for growth and development. The exact amount of time spent in interphase depends on the type of cell.

Mitosis takes up a much smaller part of the cell cycle, with cells moving through each of the four phases relatively quickly. Mitosis takes the same amount of time, regardless of cell type. Prophase is generally the longest phase of mitosis because so much has to happen. The nuclear membrane has to break down and the spindle fibers have to attach to each chromosome.

Metaphase is a relatively short phase because just one thing has to happen: the chromosomes line up at the center of the cell. Metaphase is followed by anaphase, which takes even less time to complete because it does not take long for the chromosomes to be pulled to opposite ends of the cell. Telophase is another short phase as a new nuclear membrane begins to form around the chromosomes in each half of the cell.

In plants and animals, mitosis happens frequently. This is because plants and animals begin life as a single cell. Through mitosis, that single cell divides many times, becoming many cells that all have the same copy of genetic information. Mitosis is how individual plants and animals grow and develop. For example, an onion’s roots grow as they search for water and nutrients. Onion cells generally require 12 hours for one complete cell cycle, moving from interphase through the four phases of mitosis and back to interphase.

Supports Grade 7

Science Lesson: Understanding Mitosis in Animal and Plant Cells

Once students understand the basic structure of DNA and chromosomes, they focus on the phenomena of how cells grow and then divide in mitosis to produce new daughter cells. Those new cells contain DNA from the parent cell. Cell division allows for growth, repair, and reproduction.

Science Big Ideas

  • Cells grow, develop, and pass along their genetic information in a process called a life cycle. Scientists who are interested in cells often study a cell’s life cycle.
  • One step in the cell cycle is called mitosis.Mitosis is an essential part of the cell life cycle.
  • Mitosis is cell division that results in two daughter cells with the same number and kind of chromosomes as the parent cell. Mitosis results in new, genetically identical cells.
  • Many of the cells in multicellular organisms such as plants and animals undergo mitosis frequently for growth and healing.
  • Cells are constantly changing as they go through mitosis. The ability to grow, develop, and heal means that cells cannot remain static and unchanging.

Sample Unit CTA-2
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Science Essential Questions

  • Why do cells have a cell cycle?
  • Why do cells spend most of their lives in interphase?
  • Why is it important that cells replicate their DNA during interphase?
  • What are some of the reasons that cells divide?
  • How can we tell when a cell is beginning mitosis?
  • Why do cells in mitosis spend more time in prophase than any other phase?
  • Why is it important that the chromosome pairs line up in the middle of the cell end to end?
  • How can we tell that anaphase is beginning?
  • Why do cells in plants and animals undergo mitosis so frequently?
  • How does mitosis provide evidence that cells are dynamic and always changing?

Common Science Misconceptions

Misconception: Organisms grow because cells get bigger.

Fact: Organisms grow because cells divide. 

Misconception: Cell division results in a decrease in the number of chromosomes.

Fact: In mitosis, cells divide to create exact replicas of themselves, with the same number and kind of chromosome. In meiosis, the daughter cells have half the number of chromosomes as the parent cell.

Science Vocabulary

Cell cycle : an ordered series of events that ends in cell division; consists of interphase and mitosis

Cell division : the splitting of a single cell into daughter cells, each with DNA from its parent cell

Daughter cell : a cell formed by the division of a parent cell

Interphase : the part of the cell cycle when a cell performs its normal functions

Life cycle : the series of developmental stages an organism passes through on its way from birth to death

Mitosis : a form of cell division that results in two daughter cells with the same number of chromosomes as the parent cell

Replicate : to make a copy

Lexile(R) Certified Non-Fiction Science Reading (Excerpt)

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The Bristlecone Pine

There is a tree in the White Mountains of California that scientists believe is more than 5,000 years old. This tree, a bristlecone pine, is the oldest known individual tree in the world.

Scientists who are interested in the long lifespan of the bristlecone pine have compared seeds and pollen from bristlecone pines of different ages. They found that the cells of the old trees appeared just as young as the cells of the younger trees.

No one really understands how the bristlecone pine can live so long. This is something scientists are continuing to study. But scientists know it has something to do with the life cycle of the tree’s cells. A life cycle is the series of developmental stages an organism passes through on its way from birth to death. The lifespan of a cell ranges from 1 day to more than 100 years.

All cells follow a similar pattern of development. All cells first grow, and then they divide to produce new daughter cells, which are cells formed by the division of a parent cell. Those daughter cells contain DNA from the parent cell. This ordered series of events, which moves from growth to division, is called the cell cycle.

 

The Growing Phase

A typical animal cell cycle lasts roughly 24 hours, although in some animal cells it lasts less than 8 hours, while in other kinds of cells it takes more than a year. The majority of the cell cycle is spent in interphase—the period of the time when a cell performs its normal functions. For example, a human muscle cell contracts and relaxes during interphase, enabling you to move.

New nucleotides are added to each unzipped strand of the DNA molecule: adenine (A) pairs with thymine (T) and guanine (G) pairs with cytosine (C). The two new strands are both exact replicas of the original DNA molecule. The two identical chromosomes that result from DNA replication are referred to as sister chromatids. They are linked together by the centromere. The chromosomes are not visible during interphase.

Interphase is also when the cell grows, nearly doubling its size. Finally, DNA is replicated during interphase. To replicate means to make a copy of. DNA’s structure allows it to replicate because each strand of the double helix runs in opposite directions. Before a cell divides, the twisted, tightly packed double helix unwinds and separates its two strands, unzipping down the the cell cycle middle. Each strand serves as a template for a new strand of DNA.

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The Dividing Phase

Once a cell has replicated its DNA, it gets ready to divide so it can pass along its genetic information to its offspring. Cell division refers to the splitting of a single cell into daughter cells, each with DNA from the parent cell. Cell division is a natural part of a cell’s life cycle, so all cells have proteins that tell them when to divide.

Once DNA replication happens in prokaryotic cells, a new membrane forms that will eventually divide the cell, including the duplicated DNA, in two. This process happens quickly—for example, in ideal conditions, the life cycle of bacteria occurs every 30 minutes.

The eukaryotic life cycle is more complex than the prokaryotic life cycle because eukaryotes have multiple chromosomes within a nucleus. Most plant and animal cells take between 10 and 20 hours to double in number, while some duplicate much more slowly. For example, human skin cells divide almost constantly, while nerve cells in adult animals almost never divide. .

There are several reasons why cells divide. One important reason is growth. The more cells an organism has, the larger that organism is. For example, humans start off as a single cell. By the time they are adults, they have trillions of cells. Almost all of those cells, with the exception of eggs, sperm, and red blood cells, contain the same copy of DNA because of DNA replication and cell division.

Cell division also allows cells to repair damaged cells or replace dead cells. For example, human skin cells constantly divide so they can replace damaged or dead skin cells. Muscle cells also divide frequently to replace cells damaged by exercise or injury.

 

Hands-on Science Activity

In this lesson, students use microscopes to explore the phenomena of mitosis. They identify and diagram the stages of mitosis in animal and plant cells. Students gather and analyze data from this investigation to explore the different stages of mitosis.

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Science Standards

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Download the Alignment to NGSS

Standards citation: NGSS Lead States. 2013. Next Generation Science Standards: For States, By States. Washington, DC: The National Academies Press. Neither WestEd nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it.