The science background provides teachers with more in-depth information on the phenomena students explore. Below is an excerpt from the science background section on mitosis.
Mitosis
There are several reasons why cells divide. One important reason is growth. Cell division also allows cells to repair damaged cells or replace dead cells. Finally, cells divide to reproduce, passing along genetic information to offspring.
Mitosis is a form of cell division that takes place in eukaryotic cells and results in two daughter cells, each with the same number and kind of chromosomes as the parent cell. There are four phases as a parent cell separates its replicated chromosomes into two daughter cells.
Phase 1: Prophase— When the cell is ready to divide, DNA is wrapped even more tightly, and the chromosomes become visible. Each chromosome consists of the two sister chromatids formed during replication. The nuclear membrane breaks down and the chromosomes are freed from the nucleus. Small fibers called spindle fibers begin to form on opposite sides of the cell and attach to each sister chromatid.
Phase 2: Metaphase— During metaphase, the chromosome pairs line up in the middle of the cell end-to-end. This formation ensures that each daughter cell will receive one copy of each chromosome.
Phase 3: Anaphase—Separation begins. The sister chromatids separate and the spindle fibers pull one complete set of an organism’s chromosomes to each end of the cell. For humans, 46 chromosomes move to each end of the cell. Each side receives the same number and kind of chromosomes as the parent cell.
Phase 4: Telophase—During telophase, the chromosomes reach opposite ends of the cell. Nuclear envelopes reassemble and enclose each cell’s set of chromosomes in a nucleus. The chromosomes become indistinct chromatin.
After telophase, most cells undergo a process called cytokinesis in which the rest of the cell splits apart, resulting in two separate daughter cells.
Phases in Mitosis
Cells spend more than half of their lives in interphase. This is because a lot has to happen during interphase. The cell increases in size, replicates its DNA, and builds materials needed for growth and development. The exact amount of time spent in interphase depends on the type of cell.
Mitosis takes up a much smaller part of the cell cycle, with cells moving through each of the four phases relatively quickly. Mitosis takes the same amount of time, regardless of cell type. Prophase is generally the longest phase of mitosis because so much has to happen. The nuclear membrane has to break down and the spindle fibers have to attach to each chromosome.
Metaphase is a relatively short phase because just one thing has to happen: the chromosomes line up at the center of the cell. Metaphase is followed by anaphase, which takes even less time to complete because it does not take long for the chromosomes to be pulled to opposite ends of the cell. Telophase is another short phase as a new nuclear membrane begins to form around the chromosomes in each half of the cell.
In plants and animals, mitosis happens frequently. This is because plants and animals begin life as a single cell. Through mitosis, that single cell divides many times, becoming many cells that all have the same copy of genetic information. Mitosis is how individual plants and animals grow and develop. For example, an onion’s roots grow as they search for water and nutrients. Onion cells generally require 12 hours for one complete cell cycle, moving from interphase through the four phases of mitosis and back to interphase.