Organ System Structure and Function

In this unit, students focus on the structure and function of specialized cells, tissues, and organs in the phenomena of complex multicellular organisms, and they explore how the body processes information gathered by sensory receptors. In this lesson, they develop a model for a human organ system and then observe different human cells to understand how structure influences function. This page highlights each part of this lesson.

Science Background for Teachers:

The science background section gives teachers more detailed information on the phenomena students explore in this unit. Here is an excerpt of the science background section from this lesson on the human organ system structure and function. 

Structure & Function of Cells

Every specialized cell has a unique shape that allows it to perform its specific tasks. For example, the primary job of red blood cells is to deliver oxygen to all of the cells in the body and return carbon dioxide to the lungs, where it can be released into the environment.

Red blood cells look like donuts without a hole in the middle. This shape makes it easy for gasses to move into and out of the cell because they have a large surface area. Red blood cells are also flexible, which helps them move through the body’s blood vessels, some of which are narrower than a human hair.

Red blood cells are unique among cells because they do not have a nucleus. A nucleus takes up space and increases the mass of the cell. A nucleus would mean there would be less space available for carrying oxygen and carbon dioxide, and the increased weight would make the heart have to work harder to move blood throughout the body.

Skin cells are different from red blood cells. They are part of the integumentary system, which provides a tough, physical barrier from the environment. Skin cells are layered, and each layer has a different shape. The first layers of skin cells are actually dead. The layers below are alive, and grow and reproduce frequently.

A Complex Hierarchy

Cells that are specialized for a specific function group together to form tissues. Animals (including humans) generally have four kinds of tissues: epithelial, connective, muscular, and nervous tissues. Skin cells are packed tightly together to form epithelial tissue, which serves as a barrier from the environment. Cardiac muscle cells form cardiac muscle tissue, while skeletal muscle cells form skeletal muscle tissue.

Two or more types of tissues that work together to carry out a specific function form structures called organs. Organs are made up of at least two types of tissues, and some are made up of all four. There are many different animal organs, including the heart, liver, lungs, mouth, muscles, and brain. The skin is the body’s largest organ.

Groups of organs that closely interact together to carry out specific functions are called organ systems. The immune system and the integumentary system are two organ systems. Other organ systems include the circulatory, respiratory, and digestive systems. Each system is composed of many cells and keeps the organism functioning properly.

Every organ system requires that each of its parts functions properly in order to perform its job. Organ systems also depend on other organ systems to function. For example, the digestive system is responsible for breaking down food into energy that can be used by cells in the body. It includes the mouth, esophagus, stomach, intestines, liver, and the pancreas. The digestive system breaks down complex food molecules into single glucose molecules that can be absorbed by cells in the small intestine. These cells transport the molecules into the blood stream so that other cells in the body can use them. The excretory system removes the waste.

Working Together

The blood stream that carries nutrients throughout the body is part of the circulatory system, which distributes blood, oxygen, and nutrients to the body’s cells and carries away waste products.

It includes the heart, which is the body’s hardest-working organ. The heart beats approximately 100,000 times every day. It also includes blood vessels, which are hollow tubes that serve as the body’s highways. They circulate blood from the heart to every region in the body and back again. Blood is a liquid connective tissue. It travels thousands of miles in blood vessels, carrying nutrients, water, oxygen, and waste products to and from the body’s cells.

The heart is also a muscle. Because of this, it is also part of the muscular system, which is the organ system that enables an organism to move. It is responsible for all of your body’s movement. This includes movements that you direct, including lifting your arms or walking. It also includes the beating of your heart and the movement of blood through your body. Muscle tissues contract and relax to move your body parts.

The process that breaks down complex food molecules into single glucose molecules requires oxygen. The respiratory system brings in oxygen from the environment that cells need to function, and releases carbon dioxide, a waste product. It is made up of airways, lungs, and muscles of respiration. The circulatory system distributes the oxygen and carbon dioxide throughout the body.

Finally, the nervous system has to coordinate and control all of this activity. It is made up of the brain, spinal column, sensory organs, and nerve cells (which are also called neurons).

Supports Grade 6

Science Lesson: Exploring Organ System Structure and Function

All living things are systems, made up of smaller, interacting parts that work together to support the functioning of the organism. As the number of cells increases in a multicellular organism, each cell becomes better able to perform one particular function. In this lesson, students model the relationships between cells, tissues, organs, and organ systems within the human body. 

Science Big Ideas

  • Multicellular organisms are made up of more than one kind of cell and groups of these specialized cells are designed to do one job very well. 
  • Humans are so complex that the body is made up of subsystems composed of interacting parts.
  • Each system interacts with and depends on the other systems to function properly.

Sample Unit CTA-2
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Science Essential Questions

  • Why do multi-celled organisms benefit from having specialized cells?
  • What kinds of jobs do the cells in the human body have to carry out?
  • How are tissues organized in the human body?
  • How are cells related to organ systems?
  • How does the immune system interact with the digestive system in ways that may protect some people from getting the flu?
  • How can the heart be part of both the circulatory system and the muscular system?
  • How are all of the systems, organs, tissues, and cells able to work together?

Common Science Misconceptions

Misconception: Humans are made up of one kind of cell.
Fact: Humans have about 200 different kinds of cells, which are specialized for specific functions.
Misconception: Body systems are independent of one another, and so a change to one system won’t affect other systems.
Fact: Each body system is made up of smaller parts, but the systems all interact with and depend on each other for the body to function properly.

Science Vocabulary

Circulatory System : a group of organs that distribute blood, oxygen, and nutrients to the body’s cells and carry away waste products

Digestive System : a group of organs that break down food into energy that can be used by cells in the body

Excretory System : a group of organs that remove waste from the body

Immune System : a group of organs that defend the body against infectious organisms and other harmful invaders

Organ : a structure composed of two or more tissue types that work together to carry out a specific function

Organ System : a group of closely interacting organs that carry out a specific function

Respiratory System : a group of organs that enable an organism to collect oxygen and dispose of carbon dioxide

Lexile(R) Certified Non-Fiction Science Reading (Excerpt)

Organ System Structure and Function

Getting the Flu

Every year in the fall and winter, many people get the flu. But Lamar Johnson never seems to get sick. Lamar is 44 years old, and he doesn’t think he’s ever had the flu. He eats a lot of fruits and vegetables. He wonders if this is why he seems to stay healthy when people around him get sick.

Scientists don’t know for sure what makes one person catch the flu while another person stays healthy. In 2011, a team of scientists designed an experiment to help them answer this question. They infected 17 healthy people with the flu virus. They then used different tools to study how each person’s body responded to the virus.

The scientists wanted to see how each person’s immune system reacted to the flu virus. The immune system defends the body against infectious organisms and other harmful invaders.

 

Study Results

About half of the 17 people who were infected with the flu virus got sick. The results showed that the immune systems of people who didn’t have flu symptoms responded in different ways from the immune systems of those people who got sick. Scientists hope that their results will eventually lead to therapies that could one day prevent everyone from getting the flu.

Understanding how and why people get sick is complicated. One of the reasons it is complex is that the human body is made up of many different parts. For example, it is made up of about 200 different kinds of cells. Each kind of cell has a specific function that contributes to the overall functioning of the body. Some cells digest food. Others attack harmful substances. Still others carry substances such as nutrients or oxygen around the body.

Organ System Structure and Function
 
Organ System Structure and Function

Cell Specialization

This is called specialization. Instead of every cell trying to do every job, groups of cells are specialized to do one job very well. Each group of specialized cells is more efficient than if each cell worked on its own.

For example, white blood cells are part of the immune system. They play an important role in its defensive strategy. There are different kinds of white blood cells, each with a specific function. One kind of white blood cell surrounds and breaks down anything it believes does not belong in the body. It does this in one of two ways. It either absorbs the invader or releases a chemical called an enzyme that will destroy it.

Cells that are similarly specialized for a specific function group together to form tissues. Animals including humans generally have four kinds of tissues: epithelial, connective, muscular, and nervous tissues.

 

Hands-on Science Activity

In this lesson, students create a model to investigate the hierarchical organization within the phenomena of a human organ system and analyze how different organ systems rely on each other for an organism to function. Students use the body system model they develop and analysis to explain how the body is a system of smaller interacting systems, which are themselves composed of groups of specialized cells.

Science Assessments

KnowAtom incorporates formative and summative assessments designed to make students thinking visible for deeper student-centered learning.

  • Vocabulary Check
  • Lab Checkpoints
  • Concept Check Assessment 
  • Concept Map Assessment 
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cells-to-systems-map

Science Standards

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Download the Alignment to NGSS

Standards citation: NGSS Lead States. 2013. Next Generation Science Standards: For States, By States. Washington, DC: The National Academies Press. Neither WestEd nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it.