Cell Structure and Function

In this unit, students explore the structure and function of the human body by developing models of the interactions within and between systems. In this lesson, they investigate the science phenomena of cellular hierarchy in multicellular organisms, including major organ systems and their functions. This page is a high-level extract of this lesson.

Science Background for Teachers:

Science background provides teachers with more in-depth information on the phenomena students explore in this unit. Here is an excerpt of the science background section from this lesson on cell structure and function. 

Structure & Function of Cells

Every specialized cell has a unique shape that allows it to perform its specific tasks. For example, the primary job of red blood cells is to deliver oxygen to all of the cells in the body and return carbon dioxide to the lungs, where it can be released into the environment.

Red blood cells look like donuts without a hole in the middle. This shape makes it easy for gasses to move into and out of the cell because they have a large surface area. Red blood cells are also flexible, which helps them move through the body’s blood vessels, some of which are narrower than a human hair.

Red blood cells are unique among cells because they do not have a nucleus. A nucleus takes up space and increases the mass of the cell. A nucleus would mean there would be less space available for carrying oxygen and carbon dioxide, and the increased weight would make the heart have to work harder to move blood throughout the body.

Skin cells are different from red blood cells. They are part of the integumentary system, which provides a tough, physical barrier from the environment. Skin cells are layered, and each layer has a different shape. The first layers of skin cells are actually dead. The layers below are alive, and grow and reproduce frequently.

Specialized Cells

Every cell that makes up every organ system originated from a single cell, formed when an egg cell from a female and a sperm cell from a male joined together. That single cell contained a full set of genetic information. When it reproduced (divided), it passed along that same set of genetic information to its daughter cells, which became a type of cell called stem cells. Stem cells are unspecialized, meaning they are unable to perform any of the specific functions of the body. Instead, their primary job is to create specialized cells. This process of forming specialized cells is called cell differentiation. During cell differentiation, cells develop the specific shapes, structures, and characteristics they will need to perform their specific function in the body.

The nucleus of each stem cell passes on the same full set of genetic information to each specialized cell. This means that the nucleus of a cardiac cell not only contains the genes to build a cell that pumps blood. It also contains the genes to build stomach cells that absorb nutrients and nerve cells that send electrical impulses. For a cell to become specialized, certain genes must somehow be turned on, while others remain off. Scientists still don’t know exactly what causes this process.

Supports Grade 6

Science Lesson: Discovering Cell Structure and Function

Once students understand that the human body is made up of interacting systems, they focus in this lesson on the structure and function of specific cells, analyzing how cells specialize for a specific function are structured in a way that allows them to carry out that function. 

Science Big Ideas

  • All humans begin as a single cell. By the time they are adults, humans are made up of trillions of cells specialized for specific functions. 
  • Different kinds of cells have specific requirements for carrying out their specialized jobs in the human body.

Sample Unit CTA-2
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Science Essential Questions

  • How can a human being begin as a single cell and end up with trillions of cells?
  • How can a single cell turn into different specialized cells?
  • How is the circulatory system able to carry oxygen to different parts of the body?
  • Why do red blood cells need to be flexible? Why do red blood cells need to have a lot of space within them?
  • How is the muscular system able to move different parts of your body?
  • Why do muscle cells have a lot of mitochondria?
  • How does the integumentary system provide a physical barrier for the body?

Common Science Misconceptions

Misconception: Humans are made up of one kind of cell.
Fact: Humans have about 200 different kinds of cells, which are specialized for specific functions.
Misconception: Body systems are independent of one another, and so a change to one system won’t affect other systems.
Fact: Each body system is made up of smaller parts, but the systems all interact with and depend on each other for the body to function properly.

Science Vocabulary

Cell : the smallest unit of life; makes up single-celled and multi-celled organisms

Circulatory System : a group of organs that distribute blood, oxygen, and nutrients to the body’s cells and carry away waste products

Integumentary System : a group of organs that protect the body with a tough physical barrier

Muscular System : a group of organs that enable an organism to move

Nervous System : a group of organs that act as the control center for the entire body

Tissue : a group of similarly specialized cells that perform a specific function

Lexile(R) Certified Non-Fiction Science Reading (Excerpt)

Painting Cell Structures

David Goodsell is a scientist. He is also an artist. He has combined his love of cells and art to create watercolor paintings of different cells. His work is unique because it shows the molecules that make up the different parts of each cell. These molecules are so tiny that they cannot be seen with just a microscope.

David’s paintings usually represent cellular structures magnified one million times. This is the magnification necessary to see the different molecules that make up the cell.

David uses information from several different tools to help him create his paintings. He sometimes spends weeks researching a molecule before he draws it.

Understanding the structure of cells and the molecules that make them up is important for scientists like David who study cells. “It’s like understanding any piece of machinery,” David said in an interview with the California museum Exploratorium. “You have to know what it looks like and how its different parts interact with other parts, the other molecules.”

Variety of Human Body Cells

Remember that the human body is made up of trillions of cells. There are 200 kinds of specialized cells. Each kind of cell is structured in such a way that it can perform a particular job.

Muscle cells have a very different structure from red blood cells. This is because muscle cells have a different function. Every process that requires movement in your body occurs because of the 700 muscles that make up the muscular system. Muscles always work in pairs. As one muscle contracts (shortens), its pair relaxes (lengthens). A muscle is a tissue made up of many cells called fibers. Muscle fibers are long and thin, which allows the cells to change size drastically when they contract and relax. They have a lot of mitochondria, which provide a constant supply of energy to the cells during movement. There are three kinds of muscle tissue: skeletal, cardiac, and smooth.

  • Cardiac muscle cells are only found in the heart. Cardiac muscle tissue is involuntary. This means it contracts without conscious control. It is strong because it is responsible for pumping blood throughout the body.
  • Smooth tissue is involuntary tissue that lines the inside of organs like the stomach, intestines, and blood vessels. It is much shorter than the skeletal tissue. It has a smooth, uniform appearance when viewed under the microscope. cardiac muscle cells
  • Skeletal muscle cells move parts of the bone closer to each other. Skeletal muscle tissue is the only voluntary muscle tissue in the body. These cells are long. They are made up of many long fibers that can contract and relax with great force.

Skin Cells

Skin cells are different from both red blood cells and muscle cells. They are part of the integumentary system. They work to protect the body by providing a tough physical barrier. Skin is actually the body’s largest organ. It is made up of different layers of cells that work to protect your body.

Becoming Specialized

Red blood cells, muscle cells, skin cells, and all of the other cells that make up a human came from a single cell that formed when an egg cell from a female and a sperm cell from a male joined together. That single cell contains a full set of genetic information. That single cell begins to reproduce. It develops into a type of cell called a stem cell.

Stem cells are unspecialized. This means they cannot perform the specific functions of the body. Instead, their primary job is to create specialized cells that have specific structures for carrying out different functions. This process of forming specialized cells is called cell differentiation. During cell differentiation, cells develop the specific shapes, structures, and characteristics they will need to perform their specific function in the body. Scientists still don’t know exactly what causes a stem cell to turn into a specialized cell.

When a stem cell divides, each new cell can become another type of cell with a more specialized function. In embryos, cell differentiation happens depending on where the stem cell is located. For example, those stem cells on the outer layer of the embryo form skin cells. Cell differentiation is how a single cell can become a complex organism like a human being, made up of trillions of specialized cells.

 
Cell Structure and Function
Cell Structure and Function
Cell Structure and Function
 

Hands-on Science Activity

For the main activity of this lesson, students use microscopes to investigate different human cell and tissue samples to relate the form and appearance of cells and tissues to their function. Students analyze how each cell they observe has a specific function, and its structure allows it to carry out its function within the human body.

Science Assessments

KnowAtom incorporates formative and summative assessments designed to make students thinking visible for deeper student-centered learning.

  • Vocabulary Check
  • Lab Checkpoints
  • Concept Check Assessment 
  • Concept Map Assessment 
  • And More...

cells-to-systems-map

Science Standards

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Download the Alignment to NGSS

Standards citation: NGSS Lead States. 2013. Next Generation Science Standards: For States, By States. Washington, DC: The National Academies Press. Neither WestEd nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it.